Neural Recording

Figure of model STN DBS local field potential recording.

We study the biophysics of how electric fields generated by neurons are recorded as voltage fluctuations on electrodes implanted in brain tissue. This includes single unit recordings on microelectrodes, as well as local field potential recordings on macroelectrodes.

Noor MS, McIntyre CC. Biophysical characterization of local field potential recordings from directional deep brain stimulation electrodes. Clin Neurophysiol. 2021 Jun;132(6):1321-1329. doi: 10.1016/j.clinph.2021.01.027. Epub 2021 Mar 10. PMID: 33867263; PMCID: PMC8137656.

Maling N, Lempka SF, Blumenfeld Z, Bronte-Stewart H, McIntyre CC. Biophysical basis of subthalamic local field potentials recorded from deep brain stimulation electrodes. J Neurophysiol. 2018 Oct 1;120(4):1932-1944. doi: 10.1152/jn.00067.2018. Epub 2018 Jul 18. PMID: 30020838; PMCID: PMC6230781.

Lempka SF, McIntyre CC. Theoretical analysis of the local field potential in deep brain stimulation applications. PLoS One. 2013;8(3):e59839. doi: 10.1371/journal.pone.0059839. Epub 2013 Mar 28. PMID: 23555799; PMCID: PMC3610913.